Perturbation of PI3K/Akt Signaling Affected Autophagy Modulation in Dystrophin-Deficient Myoblasts

A dystrophin-deficient myoblast cell line established from the skeletal muscle of a dystrophic mouse was used as a model. The dfd13 and C2C12 myoblasts were cultured in low mitogen conditions for ten days to induce differentiation.