The RNA Helicase Ddx21 Controls Vegfc-Driven Developmental Lymphangiogenesis by Balancing Endothelial Cell Ribosome Biogenesis and p53 Function

Scientists showed that Ddx21 was enriched in sprouting venous endothelial cells in response to Vegfc–Flt4 signalling. Ddx21 function was essential for Vegfc–Flt4-driven endothelial cell proliferation.