Neutrophils Prevent Rectal Bleeding in Ulcerative Colitis by Peptidyl-Arginine Deiminase-4-Dependent Immunothrombosis

The authors used high-resolution endoscopy and colon tissue samples of active ulcerative colitis as well as experimental models of physical and chemical mucosal damage in mice deficient for peptidyl-arginine deiminase-4, gnotobiotic mice and controls.