Circulating CD8⁺ Mucosal-Associated Invariant T Cells Correlate with Improved Treatment Responses and Overall Survival in Anti-PD-1-Treated Melanoma Patients

Investigators analyzed the frequency and functional profile of circulating and tumor-infiltrating mucosal-associated invariant T cells in human melanoma patients. Using flow cytometry, they compared these across metastatic sites and between ICI responders vs. non-responders as well as healthy donors.