Dapagliflozin Exerts Anti-inflammatory Effects via Inhibition of LPS-Induced TLR-4 Overexpression and NF-κB Activation in Human Endothelial Cells and Differentiated Macrophages

The authors assessed the direct anti-inflammatory effects of sodium-glucose co-transporter 2 inhibitors dapagliflozin on two cell types involved in the process of atherogenesis.