The HDAC2/SP1/miR-205 Feedback Loop Contributes to Tubular Epithelial Cell Extracellular Matrix Production in Diabetic Kidney Disease

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The authors described a novel feedback loop composed of histone deacetylase 2 (HDAC2) and miR-205 that regulated ECM production in tubular epithelial cells in individuals with diabetic kidney disease.
[Clinical Science]
Abstract