ICAM-1-Mediated Adhesion Is a Prerequisite for Exosome-Induced T Cell Suppression

Scientists reported that the adhesion molecule intercellular adhesion molecule 1 (ICAM-1) co-localized with programmed death ligand 1 (PD-L1) on the exosomes; both ICAM-1 and PD-L1 were upregulated by interferon-γ.