Developmentally Distinct CD4⁺ Treg Lineages Shape the CD8⁺ T Cell Response to Acute Listeria Infection

Investigators found that acute Listeria monocytogenes infection produced a phenotypically and functionally complex Treg response comprising two separate suppressor cell subpopulations, with an early Treg peak occurring at 24 hour post-infection and a later peak arising by day seven.