Immunosuppressive TREM2(⁺) Macrophages Are Associated with Undesirable Prognosis and Responses to Anti-PD-1 Immunotherapy in Non-Small Cell Lung Cancer

Large cohorts of non-small cell lung cancer patients from The Cancer Genome Atlas and a single-cell sequencing dataset were integrated to illustrate immunosuppressive phenotypes of tumor-associated macrophages, followed by experimental verification.