Exosomes from Primed MSCs Can Educate Monocytes as a Cellular Therapy for Hematopoietic Acute Radiation Syndrome

Human monocytes were educated by exosomes from lipopolysaccharide-primed mesenchymal stem cells (MSCs) and compared to monocytes educated by unprimed MSCs and uneducated monocytes to assess survival and clinical improvement in a xenogeneic mouse model of acute radiation syndrome.