Exosomes from Primed MSCs Can Educate Monocytes as a Cellular Therapy for Hematopoietic Acute Radiation Syndrome

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Human monocytes were educated by exosomes from lipopolysaccharide-primed mesenchymal stem cells (MSCs) and compared to monocytes educated by unprimed MSCs and uneducated monocytes to assess survival and clinical improvement in a xenogeneic mouse model of acute radiation syndrome.
[Stem Cell Research & Therapy]
Forsberg, M. H., Kink, J. A., Thickens, A. S., Lewis, B. M., Childs, C. J., Hematti, P., & Capitini, C. M. (2021). Exosomes from primed MSCs can educate monocytes as a cellular therapy for hematopoietic acute radiation syndrome. Stem Cell Research & Therapy, 12(1), 459. https://doi.org/10.1186/s13287-021-02491-7 Cite
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