Scientists discovered that glioblastoma cells exhibited features indicative of malignant progression and were present in a hypoxic environment.
[Cell Death & Disease]
6807162 {6807162:LTD2LFE4} apa 50 1 160451 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/ %7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-447dc9ec71dead7b05c8e766a3bf8047%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22LTD2LFE4%22%2C%22library%22%3A%7B%22id%22%3A6807162%7D%2C%22meta%22%3A%7B%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Ci%3EHIF1%26%23x3B1%3B%5C%2FHIF2%26%23x3B1%3B%26%23x2013%3BSox2%5C%2FKlf4%20promotes%20the%20malignant%20progression%20of%20glioblastoma%20via%20the%20EGFR%26%23x2013%3BPI3K%5C%2FAKT%20signalling%20pathway%20with%20positive%20feedback%20under%20hypoxia%20%7C%20Cell%20Death%20%26amp%3B%20Disease%3C%5C%2Fi%3E.%20%28n.d.%29.%20Retrieved%20March%2024%2C%202021%2C%20from%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41419-021-03598-8%27%3Ehttps%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41419-021-03598-8%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D6807162%26amp%3Bitem_key%3DLTD2LFE4%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22webpage%22%2C%22title%22%3A%22HIF1%5Cu03b1%5C%2FHIF2%5Cu03b1%5Cu2013Sox2%5C%2FKlf4%20promotes%20the%20malignant%20progression%20of%20glioblastoma%20via%20the%20EGFR%5Cu2013PI3K%5C%2FAKT%20signalling%20pathway%20with%20positive%20feedback%20under%20hypoxia%20%7C%20Cell%20Death%20%26%20Disease%22%2C%22creators%22%3A%5B%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41419-021-03598-8%22%2C%22language%22%3A%22%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-03-24T17%3A13%3A24Z%22%7D%7D%5D%7DHIF1α/HIF2α–Sox2/Klf4 promotes the malignant progression of glioblastoma via the EGFR–PI3K/AKT signalling pathway with positive feedback under hypoxia | Cell Death & Disease. (n.d.). Retrieved March 24, 2021, from
https://www.nature.com/articles/s41419-021-03598-8 Cite 
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