C3G Downregulation Induces the Acquisition of a Mesenchymal Phenotype That Enhances Aggressiveness of Glioblastoma Cells

By
Justin.choi
-
0
36
The authors report that C3G downregulation promoted the acquisition of a more mesenchymal phenotype that enhanced the migratory and invasive capacity of glioblastoma cells.
[Cell Death & Disease]
6445212 {6445212:NWUGX4W9} 1 apa 50 default 1 160872 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22NWUGX4W9%22%2C%22library%22%3A%7B%22id%22%3A6445212%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Manzano%20et%20al.%22%2C%22parsedDate%22%3A%222021-04-06%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%26lt%3Bdiv%20class%3D%26quot%3Bcsl-bib-body%26quot%3B%20style%3D%26quot%3Bline-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%26quot%3B%26gt%3B%5Cn%20%20%26lt%3Bdiv%20class%3D%26quot%3Bcsl-entry%26quot%3B%26gt%3BManzano%2C%20S.%2C%20Gutierrez-Uzquiza%2C%20A.%2C%20Bragado%2C%20P.%2C%20Sequera%2C%20C.%2C%20Herranz%2C%20%26%23xD3%3B.%2C%20Rodrigo-Faus%2C%20M.%2C%20Jauregui%2C%20P.%2C%20Morgner%2C%20S.%2C%20Rubio%2C%20I.%2C%20Guerrero%2C%20C.%2C%20%26amp%3B%20Porras%2C%20A.%20%282021%29.%20C3G%20downregulation%20induces%20the%20acquisition%20of%20a%20mesenchymal%20phenotype%20that%20enhances%20aggressiveness%20of%20glioblastoma%20cells.%20%26lt%3Bi%26gt%3BCell%20Death%20%26amp%3B%20Disease%26lt%3B%5C%2Fi%26gt%3B%2C%20%26lt%3Bi%26gt%3B12%26lt%3B%5C%2Fi%26gt%3B%284%29%2C%201%26%23x2013%3B17.%20%26lt%3Ba%20class%3D%26%23039%3Bzp-DOIURL%26%23039%3B%20href%3D%26%23039%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41419-021-03631-w%26%23039%3B%26gt%3Bhttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41419-021-03631-w%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3Ba%20title%3D%26%23039%3BCite%20in%20RIS%20Format%26%23039%3B%20class%3D%26%23039%3Bzp-CiteRIS%26%23039%3B%20data-zp-cite%3D%26%23039%3Bapi_user_id%3D6445212%26amp%3Bitem_key%3DNWUGX4W9%26%23039%3B%20href%3D%26%23039%3Bjavascript%3Avoid%280%29%3B%26%23039%3B%26gt%3BCite%26lt%3B%5C%2Fa%26gt%3B%20%26lt%3B%5C%2Fdiv%26gt%3B%5Cn%26lt%3B%5C%2Fdiv%26gt%3B%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22C3G%20downregulation%20induces%20the%20acquisition%20of%20a%20mesenchymal%20phenotype%20that%20enhances%20aggressiveness%20of%20glioblastoma%20cells%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sara%22%2C%22lastName%22%3A%22Manzano%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alvaro%22%2C%22lastName%22%3A%22Gutierrez-Uzquiza%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paloma%22%2C%22lastName%22%3A%22Bragado%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Celia%22%2C%22lastName%22%3A%22Sequera%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22%5Cu00d3scar%22%2C%22lastName%22%3A%22Herranz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mar%5Cu00eda%22%2C%22lastName%22%3A%22Rodrigo-Faus%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Patricia%22%2C%22lastName%22%3A%22Jauregui%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Morgner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ignacio%22%2C%22lastName%22%3A%22Rubio%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carmen%22%2C%22lastName%22%3A%22Guerrero%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Almudena%22%2C%22lastName%22%3A%22Porras%22%7D%5D%2C%22abstractNote%22%3A%22%5Cu476c%5Cu696f%5Cu626c%5Cu6173%5Cu746f%5Cu6d61%5Cu2028%5Cu4742%5Cu4d29%5Cu2069%5Cu7320%5Cu7468%5Cu6520%5Cu6d6f%5Cu7374%5Cu2061%5Cu6767%5Cu7265%5Cu7373%5Cu6976%5Cu6520%5Cu7475%5Cu6d6f%5Cu7220%5Cu6672%5Cu6f6d%5Cu2074%5Cu6865%5Cu2063%5Cu656e%5Cu7472%5Cu616c%5Cu206e%5Cu6572%5Cu766f%5Cu7573%5Cu2073%5Cu7973%5Cu7465%5Cu6d20%5Cu2843%5Cu4e53%5Cu292e%5Cu2054%5Cu6865%5Cu2063%5Cu7572%5Cu7265%5Cu6e74%5Cu206c%5Cu6163%5Cu6b20%5Cu6f66%5Cu2065%5Cu6666%5Cu6963%5Cu6965%5Cu6e74%5Cu2074%5Cu6865%5Cu7261%5Cu7069%5Cu6573%5Cu206d%5Cu616b%5Cu6573%5Cu2065%5Cu7373%5Cu656e%5Cu7469%5Cu616c%5Cu2074%5Cu6f20%5Cu6669%5Cu6e64%5Cu206e%5Cu6577%5Cu2074%5Cu7265%5Cu6174%5Cu6d65%5Cu6e74%5Cu2073%5Cu7472%5Cu6174%5Cu6567%5Cu6965%5Cu732e%5Cu2043%5Cu3347%5Cu2c20%5Cu6120%5Cu6775%5Cu616e%5Cu696e%5Cu6520%5Cu6e75%5Cu636c%5Cu656f%5Cu7469%5Cu6465%5Cu2065%5Cu7863%5Cu6861%5Cu6e67%5Cu6520%5Cu6661%5Cu6374%5Cu6f72%5Cu2066%5Cu6f72%5Cu2073%5Cu6f6d%5Cu6520%5Cu5261%5Cu7320%5Cu7072%5Cu6f74%5Cu6569%5Cu6e73%5Cu2c20%5Cu706c%5Cu6179%5Cu7320%5Cu6120%5Cu6475%5Cu616c%5Cu2072%5Cu6f6c%5Cu6520%5Cu696e%5Cu2063%5Cu616e%5Cu6365%5Cu722c%5Cu2062%5Cu7574%5Cu2069%5Cu7473%5Cu2066%5Cu756e%5Cu6374%5Cu696f%5Cu6e20%5Cu696e%5Cu2047%5Cu424d%5Cu2072%5Cu656d%5Cu6169%5Cu6e73%5Cu2075%5Cu6e6b%5Cu6e6f%5Cu776e%5Cu2e20%5Cu4461%5Cu7461%5Cu6261%5Cu7365%5Cu2061%5Cu6e61%5Cu6c79%5Cu7365%5Cu7320%5Cu7265%5Cu7665%5Cu616c%5Cu6564%5Cu2061%5Cu2072%5Cu6564%5Cu7563%5Cu6564%5Cu2043%5Cu3347%5Cu206d%5Cu524e%5Cu4120%5Cu6578%5Cu7072%5Cu6573%5Cu7369%5Cu6f6e%5Cu2069%5Cu6e20%5Cu4742%5Cu4d20%5Cu7061%5Cu7469%5Cu656e%5Cu7420%5Cu7361%5Cu6d70%5Cu6c65%5Cu732e%5Cu2043%5Cu3347%5Cu2070%5Cu726f%5Cu7465%5Cu696e%5Cu206c%5Cu6576%5Cu656c%5Cu7320%5Cu7765%5Cu7265%5Cu2061%5Cu6c73%5Cu6f20%5Cu6465%5Cu6372%5Cu6561%5Cu7365%5Cu6420%5Cu696e%5Cu2061%5Cu2070%5Cu616e%5Cu656c%5Cu206f%5Cu6620%5Cu6875%5Cu6d61%5Cu6e20%5Cu4742%5Cu4d20%5Cu6365%5Cu6c6c%5Cu206c%5Cu696e%5Cu6573%5Cu2061%5Cu7320%5Cu636f%5Cu6d70%5Cu6172%5Cu6564%5Cu2074%5Cu6f20%5Cu6173%5Cu7472%5Cu6f63%5Cu7974%5Cu6573%5Cu2e20%5Cu4261%5Cu7365%5Cu6420%5Cu6f6e%5Cu2074%5Cu6869%5Cu732c%5Cu2077%5Cu6520%5Cu6368%5Cu6172%5Cu6163%5Cu7465%5Cu7269%5Cu7a65%5Cu6420%5Cu4333%5Cu4720%5Cu6675%5Cu6e63%5Cu7469%5Cu6f6e%5Cu2069%5Cu6e20%5Cu4742%5Cu4d20%5Cu7573%5Cu696e%5Cu6720%5Cu696e%5Cu2076%5Cu6974%5Cu726f%5Cu2061%5Cu6e64%5Cu2069%5Cu6e20%5Cu7669%5Cu766f%5Cu2068%5Cu756d%5Cu616e%5Cu2047%5Cu424d%5Cu206d%5Cu6f64%5Cu656c%5Cu732e%5Cu2057%5Cu6520%5Cu7265%5Cu706f%5Cu7274%5Cu2068%5Cu6572%5Cu6520%5Cu7468%5Cu6174%5Cu2043%5Cu3347%5Cu2064%5Cu6f77%5Cu6e72%5Cu6567%5Cu756c%5Cu6174%5Cu696f%5Cu6e20%5Cu7072%5Cu6f6d%5Cu6f74%5Cu6564%5Cu2074%5Cu6865%5Cu2061%5Cu6371%5Cu7569%5Cu7369%5Cu7469%5Cu6f6e%5Cu206f%5Cu6620%5Cu6120%5Cu6d6f%5Cu7265%5Cu206d%5Cu6573%5Cu656e%5Cu6368%5Cu796d%5Cu616c%5Cu2070%5Cu6865%5Cu6e6f%5Cu7479%5Cu7065%5Cu2074%5Cu6861%5Cu7420%5Cu656e%5Cu6861%5Cu6e63%5Cu6564%5Cu2074%5Cu6865%5Cu206d%5Cu6967%5Cu7261%5Cu746f%5Cu7279%5Cu2061%5Cu6e64%5Cu2069%5Cu6e76%5Cu6173%5Cu6976%5Cu6520%5Cu6361%5Cu7061%5Cu6369%5Cu7479%5Cu206f%5Cu6620%5Cu4742%5Cu4d20%5Cu6365%5Cu6c6c%5Cu732e%5Cu2054%5Cu6869%5Cu7320%5Cu6661%5Cu6369%5Cu6c69%5Cu7461%5Cu7465%5Cu7320%5Cu666f%5Cu6369%5Cu2066%5Cu6f72%5Cu6d61%5Cu7469%5Cu6f6e%5Cu2069%5Cu6e20%5Cu616e%5Cu6368%5Cu6f72%5Cu6167%5Cu652d%5Cu6465%5Cu7065%5Cu6e64%5Cu656e%5Cu7420%5Cu616e%5Cu6420%5Cu2d69%5Cu6e64%5Cu6570%5Cu656e%5Cu6465%5Cu6e74%5Cu2067%5Cu726f%5Cu7774%5Cu6820%5Cu6173%5Cu7361%5Cu7973%5Cu2061%5Cu6e64%5Cu2074%5Cu6865%5Cu2067%5Cu656e%5Cu6572%5Cu6174%5Cu696f%5Cu6e20%5Cu6f66%5Cu206c%5Cu6172%5Cu6765%5Cu7220%5Cu7475%5Cu6d6f%5Cu7273%5Cu2069%5Cu6e20%5Cu7865%5Cu6e6f%5Cu6772%5Cu6166%5Cu7473%5Cu2061%5Cu6e64%5Cu2063%5Cu6869%5Cu636b%5Cu2063%5Cu686f%5Cu7269%5Cu6f61%5Cu6c6c%5Cu616e%5Cu746f%5Cu6963%5Cu206d%5Cu656d%5Cu6272%5Cu616e%5Cu6520%5Cu2843%5Cu414d%5Cu2920%5Cu6173%5Cu7361%5Cu7973%5Cu2c20%5Cu6275%5Cu7420%5Cu7769%5Cu7468%5Cu2061%5Cu206c%5Cu6f77%5Cu6572%5Cu2063%5Cu656c%5Cu6c20%5Cu6465%5Cu6e73%5Cu6974%5Cu792c%5Cu2061%5Cu7320%5Cu7072%5Cu6f6c%5Cu6966%5Cu6572%5Cu6174%5Cu696f%5Cu6e20%5Cu7761%5Cu7320%5Cu7265%5Cu6475%5Cu6365%5Cu642e%5Cu204d%5Cu6563%5Cu6861%5Cu6e69%5Cu7374%5Cu6963%5Cu616c%5Cu6c79%5Cu2c20%5Cu4333%5Cu4720%5Cu6b6e%5Cu6f63%5Cu6b2d%5Cu646f%5Cu776e%5Cu2069%5Cu6d70%5Cu6169%5Cu7273%5Cu2045%5Cu4746%5Cu5220%5Cu7369%5Cu676e%5Cu616c%5Cu696e%5Cu6720%5Cu6279%5Cu2072%5Cu6564%5Cu7563%5Cu696e%5Cu6720%5Cu6365%5Cu6c6c%5Cu2073%5Cu7572%5Cu6661%5Cu6365%5Cu2045%5Cu4746%5Cu5220%5Cu7468%5Cu726f%5Cu7567%5Cu6820%5Cu7265%5Cu6379%5Cu636c%5Cu696e%5Cu6720%5Cu696e%5Cu6869%5Cu6269%5Cu7469%5Cu6f6e%5Cu2c20%5Cu7768%5Cu696c%5Cu6520%5Cu7570%5Cu7265%5Cu6775%5Cu6c61%5Cu7469%5Cu6e67%5Cu2074%5Cu6865%5Cu2061%5Cu6374%5Cu6976%5Cu6174%5Cu696f%5Cu6e20%5Cu6f66%5Cu2073%5Cu6576%5Cu6572%5Cu616c%5Cu206f%5Cu7468%5Cu6572%5Cu2072%5Cu6563%5Cu6570%5Cu746f%5Cu7220%5Cu7479%5Cu726f%5Cu7369%5Cu6e65%5Cu206b%5Cu696e%5Cu6173%5Cu6573%5Cu2028%5Cu5254%5Cu4b73%5Cu2920%5Cu7468%5Cu6174%5Cu206d%5Cu6967%5Cu6874%5Cu2070%5Cu726f%5Cu6d6f%5Cu7465%5Cu2069%5Cu6e76%5Cu6173%5Cu696f%5Cu6e2e%5Cu2049%5Cu6e20%5Cu7061%5Cu7274%5Cu6963%5Cu756c%5Cu6172%5Cu2c20%5Cu4647%5Cu4632%5Cu2c20%5Cu6c69%5Cu6b65%5Cu6c79%5Cu2061%5Cu6374%5Cu696e%5Cu6720%5Cu7468%5Cu726f%5Cu7567%5Cu6820%5Cu4647%5Cu4652%5Cu312c%5Cu2070%5Cu726f%5Cu6d6f%5Cu7465%5Cu6420%5Cu696e%5Cu7661%5Cu7369%5Cu6f6e%5Cu206f%5Cu6620%5Cu4333%5Cu472d%5Cu7369%5Cu6c65%5Cu6e63%5Cu6564%5Cu2047%5Cu424d%5Cu2063%5Cu656c%5Cu6c73%5Cu2e20%5Cu4d6f%5Cu7265%5Cu6f76%5Cu6572%5Cu2c20%5Cu4552%5Cu4b73%5Cu206d%5Cu6564%5Cu6961%5Cu7465%5Cu2074%5Cu6869%5Cu7320%5Cu696e%5Cu7661%5Cu7369%5Cu7665%5Cu6e65%5Cu7373%5Cu2c20%5Cu626f%5Cu7468%5Cu2069%5Cu6e20%5Cu7265%5Cu7370%5Cu6f6e%5Cu7365%5Cu2074%5Cu6f20%5Cu4647%5Cu4632%5Cu2d20%5Cu616e%5Cu6420%5Cu7365%5Cu7275%5Cu6d2d%5Cu696e%5Cu6475%5Cu6365%5Cu6420%5Cu6368%5Cu656d%5Cu6f61%5Cu7474%5Cu7261%5Cu6374%5Cu696f%5Cu6e2e%5Cu2049%5Cu6e20%5Cu636f%5Cu6e63%5Cu6c75%5Cu7369%5Cu6f6e%5Cu2c20%5Cu6f75%5Cu7220%5Cu6461%5Cu7461%5Cu2073%5Cu686f%5Cu7720%5Cu7468%5Cu6520%5Cu6469%5Cu7374%5Cu696e%5Cu6374%5Cu2064%5Cu6570%5Cu656e%5Cu6465%5Cu6e63%5Cu7920%5Cu6f66%5Cu2047%5Cu424d%5Cu2074%5Cu756d%5Cu6f72%5Cu7320%5Cu6f6e%5Cu2043%5Cu3347%5Cu2066%5Cu6f72%5Cu2045%5Cu4746%5Cu2f45%5Cu4746%5Cu5220%5Cu7369%5Cu676e%5Cu616c%5Cu696e%5Cu6720%5Cu7665%5Cu7273%5Cu7573%5Cu206f%5Cu7468%5Cu6572%5Cu2052%5Cu544b%5Cu732c%5Cu2073%5Cu7567%5Cu6765%5Cu7374%5Cu696e%5Cu6720%5Cu7468%5Cu6174%5Cu2061%5Cu7373%5Cu6573%5Cu7369%5Cu6e67%5Cu2043%5Cu3347%5Cu206c%5Cu6576%5Cu656c%5Cu7320%5Cu6d61%5Cu7920%5Cu6469%5Cu7363%5Cu7269%5Cu6d69%5Cu6e61%5Cu7465%5Cu2047%5Cu424d%5Cu2070%5Cu6174%5Cu6965%5Cu6e74%5Cu2072%5Cu6573%5Cu706f%5Cu6e64%5Cu6572%5Cu7320%5Cu746f%5Cu2064%5Cu6966%5Cu6665%5Cu7265%5Cu6e74%5Cu2052%5Cu544b%5Cu2069%5Cu6e68%5Cu6962%5Cu6974%5Cu696f%5Cu6e20%5Cu7072%5Cu6f74%5Cu6f63%5Cu6f6c%5Cu732e%5Cu2048%5Cu656e%5Cu6365%5Cu2c20%5Cu7061%5Cu7469%5Cu656e%5Cu7473%5Cu2077%5Cu6974%5Cu6820%5Cu6120%5Cu6c6f%5Cu7720%5Cu4333%5Cu4720%5Cu6578%5Cu7072%5Cu6573%5Cu7369%5Cu6f6e%5Cu206d%5Cu6967%5Cu6874%5Cu206e%5Cu6f74%5Cu2072%5Cu6573%5Cu706f%5Cu6e64%5Cu2074%5Cu6f20%5Cu4547%5Cu4652%5Cu2069%5Cu6e68%5Cu6962%5Cu6974%5Cu6f72%5Cu732e%22%2C%22date%22%3A%222021-04-06%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41419-021-03631-w%22%2C%22ISSN%22%3A%222041-4889%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41419-021-03631-w%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-04-06T15%3A58%3A43Z%22%7D%7D%5D%7D
Manzano, S., Gutierrez-Uzquiza, A., Bragado, P., Sequera, C., Herranz, Ó., Rodrigo-Faus, M., Jauregui, P., Morgner, S., Rubio, I., Guerrero, C., & Porras, A. (2021). C3G downregulation induces the acquisition of a mesenchymal phenotype that enhances aggressiveness of glioblastoma cells. Cell Death & Disease, 12(4), 1–17. https://doi.org/10.1038/s41419-021-03631-w Cite
Full Article