SNAI1-Mediated Transcriptional Regulation of Epithelial-to-Mesenchymal Transition Genes in Breast Cancer Stem Cells

Researchers performed in silico analysis of microarray data from luminal, Her2+, and triple-negative breast cancer cell lines and identified 15 relatively unexplored epithelial-to-mesenchymal (EMT)-related differentially expressed genes along with the markedly high expression of EMT-transcription factor, SNAI1.