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Matrix Stiffness Modulates Hepatic Stellate Cell Activation into Tumor-Promoting Myofibroblasts via E2F3-Dependent Signaling and Regulates Malignant Progression

Justin.choi

December 7, 2021

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Scientists demonstrated that stiffness contributed to mechanosignal transduction in hepatic stellate cells, which promoted hepatocellular carcinoma cells growth and metastasis through secretion of FGF2.

[Cell Death & Disease]

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