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Pulmonary Cell NewsScientists integrated in situ Hi-C and nine additional omics layers. Beyond conventional active and inactive compartments, they uncovered a highly-dynamic intermediate compartment enriched in poised and polycomb-repressed chromatin.
[Nature Communications]
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Vilarrasa-Blasi, R., Soler-Vila, P., Verdaguer-Dot, N., Russiñol, N., Di Stefano, M., Chapaprieta, V., Clot, G., Farabella, I., Cuscó, P., Kulis, M., Agirre, X., Prosper, F., Beekman, R., Beà, S., Colomer, D., Stunnenberg, H. G., Gut, I., Campo, E., Marti-Renom, M. A., & Martin-Subero, J. I. (2021). Dynamics of genome architecture and chromatin function during human B cell differentiation and neoplastic transformation. Nature Communications, 12(1), 651. https://doi.org/10.1038/s41467-020-20849-y Cite
