Scientists review the roles of multiple immunological mechanisms and therapeutic targets related to the inflammation associated with fatty liver diseases and the differences in the progression of alcoholic liver disease and nonalcoholic fatty liver disease. Multiple cell types in the liver, including macrophages, neutrophils, other immune cell types and hepatocytes, are involved in fatty liver disease inflammation.
[Cellular & Molecular Immunology]
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Wang, H., Mehal, W., Nagy, L. E., & Rotman, Y. (2020). Immunological mechanisms and therapeutic targets of fatty liver diseases. Cellular & Molecular Immunology, 1–19. https://doi.org/10.1038/s41423-020-00579-3 Cite