ECM1 Modified HF-MSCs Targeting HSC Attenuate Liver Cirrhosis by Inhibiting the TGF-β/Smad Signaling Pathway

To improve the effectiveness of naïve hair follicle-derived-MSC (HF-MSC) treatments on liver cirrhosis (LC), the authors used bioinformatic tools to identify an exogenous gene targeting hepatic stellate cells (HSCs) among the differentially expressed genes in LC to modify HF-MSCs.