A GATA4-Regulated Secretory Program Suppresses Tumors through Recruitment of Cytotoxic CD8 T Cells

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Investigators found that GATA4 promoted non-cell autonomous tumor suppression in multiple model systems. Mechanistically, they showed that Gata4-dependent tumor suppression required cytotoxic CD8 T cells and partially required the secreted chemokine CCL2.
[Nature Communications]
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