Scientists developed an impedance system to measure the change in electrical resistance of 3D HIOs depending on the integrity of the intestinal epithelial cell membrane, which can reflect functionality and maturity.
[Analytical Chemistry]
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Ahn, J., Jung, K. B., Kwon, O., Choi, M.-S., Ahn, J.-H., Han, H.-Y., Jung, C.-R., Yoon, S., Son, M.-Y., & Oh, J.-H. (2021). Impedance Measurement System for Assessing the Barrier Integrity of Three-Dimensional Human Intestinal Organoids. Analytical Chemistry. https://doi.org/10.1021/acs.analchem.1c00655 Cite