(-)-Epicatechin Acts as a Potent Agonist of the Membrane Androgen Receptor, ZIP9 (SLC39A9), to Promote Apoptosis of Breast and Prostate Cancer Cells

The authors investigated the potential interactions of (-)-epicatechin and (+)-catechin with the membrane androgen receptor, ZIP9 (SLC39A9), which mediates androgen induction of apoptosis in human breast and prostate cancer cells.