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dendritic cells

Membrane Vesicles of Lacticaseibacillus Rhamnosus JB-1 Contain Immunomodulatory Lipoteichoic Acid and Are Endocytosed by Intestinal Epithelial Cells

[Scientific Reports] Scientists demonstrated that membrane vesicles from Lacticaseibacillus rhamnosus JB-1 were endocytosed in a likely clathrin-dependent manner by both mouse and human intestinal epithelial cells (IECs) in vitro and by mouse IEC in vivo.

Single Cell Analysis of Mouse and Human Prostate Reveals Novel Fibroblasts with Specialized Distribution and Microenvironment Interactions

[Journal of Pathology] Using single cell RNA-sequencing, investigators identified and validated the in situ localization of three smooth muscle subtypes and two novel fibroblast subtypes in human prostate.

Interactions of Nasal Epithelium with Macrophages and Dendritic Cells Variously Alter Urban PM-Induced Inflammation in Healthy, Asthma and COPD

[Scientific Reports] Scientists characterized the immune processes induced by the epithelium after urban particulate matter exposure in special regard to interactions with monocyte-derived dendritic cells and monocyte-derived macrophages in obstructive lung diseases.

Targeted Delivery of Regulatory Macrophages to Lymph Nodes Interferes with T Cell Priming by Preventing the Formation of Stable Immune Synapses

[Cell Reports] Delivery of regulatory macrophages (Mregs) completely abolished the priming of cognate CD8 cells and strongly reduced delayed-type hypersensitivity reactions. Mreg-mediated T cell suppression requires cell-cell contact-regulated nitric oxide production.

Follicular Lymphoma Triggers Phenotypic and Functional Remodeling of the Human Lymphoid Stromal Cell Landscape

[Immunity] Researchers examined the effect of B cell stimuli on lymphoid stromal cells in follicular lymphoma (FL). FL B cells interacted primarily with CD49a+ fibroblastic reticular cells.

Expansion of Tumor-Associated Treg Cells upon Disruption of a CTLA-4-Dependent Feedback Loop

[Cell] Researchers found that the polyclonal Treg cell repertoire is pre-enriched to recognize antigens presented by tumor-associated conventional dendritic cells.

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