Follicular Lymphoma Triggers Phenotypic and Functional Remodeling of the Human Lymphoid Stromal Cell Landscape

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Researchers examined the effect of B cell stimuli on lymphoid stromal cells in follicular lymphoma (FL). FL B cells interacted primarily with CD49a+ fibroblastic reticular cells.
[Immunity]
Mourcin, F., Verdière, L., Roulois, D., Amin, R., Lamaison, C., Sibut, V., Thamphya, B., Pangault, C., Monvoisin, C., Huet, S., Seffals, M., Baulande, S., Mechta-Grigoriou, F., Legoix, P., Rossille, D., Guirriec, M., Léonard, S., Cartron, G., Salles, G., … Tarte, K. (2021). Follicular lymphoma triggers phenotypic and functional remodeling of the human lymphoid stromal cell landscape. Immunity, 0(0). https://doi.org/10.1016/j.immuni.2021.05.019 Cite
AbstractGraphical Abstract