FYN–TRAF3IP2 Induces NF-κB Signaling-Driven Peripheral T-Cell Lymphoma

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Consistent with a driver oncogenic role, FYN–TRAF3IP2 expression in hematopoietic progenitors induced NF-κB-driven T-cell transformation in mice and cooperated with loss of the Tet2 tumor suppressor in peripheral T-cell lymphoma development.
[Nature Cancer]
FYN – TRAF3IP2 induces NF-κB signaling-driven peripheral T-cell lymphoma | Nature Cancer. (n.d.). Retrieved January 22, 2021, from https://www.nature.com/articles/s43018-020-00161-w Cite
Abstract