DEFA5 directly bound with BMI‐1, which subsequently decreased its binding at the CDKN2a locus and upregulated the expression of two cyclin‐dependent kinase inhibitors, p16 and p19.
[Cancer Science]
6606345 E6DIZARL items 1 apa 0 default asc 1 158474 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/ %7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-99590fc3a55c869b478248004173e16a%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22E6DIZARL%22%2C%22library%22%3A%7B%22id%22%3A6606345%7D%2C%22meta%22%3A%7B%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Ci%3EThe%20inhibitory%20Effect%20of%20human%20DEFA5%20in%20Growth%20of%20gastric%20cancer%20by%20targeting%20BMI%26%23x2010%3B1%20-%20Wu%20-%20-%20Cancer%20Science%20-%20Wiley%20Online%20Library%3C%5C%2Fi%3E.%20%28n.d.%29.%20Retrieved%20January%2028%2C%202021%2C%20from%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2F10.1111%5C%2Fcas.14827%27%3Ehttps%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2F10.1111%5C%2Fcas.14827%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D6606345%26amp%3Bitem_key%3DE6DIZARL%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22webpage%22%2C%22title%22%3A%22The%20inhibitory%20Effect%20of%20human%20DEFA5%20in%20Growth%20of%20gastric%20cancer%20by%20targeting%20BMI%5Cu20101%20-%20Wu%20-%20-%20Cancer%20Science%20-%20Wiley%20Online%20Library%22%2C%22creators%22%3A%5B%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2F10.1111%5C%2Fcas.14827%22%2C%22language%22%3A%22%22%2C%22deleted%22%3A1%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-01-28T18%3A28%3A11Z%22%7D%7D%5D%7DThe inhibitory Effect of human DEFA5 in Growth of gastric cancer by targeting BMI‐1 - Wu - - Cancer Science - Wiley Online Library. (n.d.). Retrieved January 28, 2021, from
https://onlinelibrary.wiley.com/doi/10.1111/cas.14827 Cite 
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