Investigators found that GPR126 had higher expression in most colorectal cancer cell lines than in normal colon epithelial cell lines, and higher expression levels in colorectal cancer tissues than in normal adjacent colon tissues.
[Cancer Science]
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Cui, H., Yu, W., Yu, M., Luo, Y., Yang, M., Cong, R., Chu, X., Gao, G., & Zhong, M. (n.d.). GPR126 regulates colorectal cancer cell proliferation by mediating HDAC2 and GLI2 expression. Cancer Science, n/a(n/a). https://doi.org/https://doi.org/10.1111/cas.14868 Cite