Scientists investigated the effect of Gli2 on liver fibrogenesis and its possible mechanism using conditional knockout Gli2 mice and hepatic stellate cell models.
[American Journal of Physiology-Gastrointestinal and Liver Physiology]
6606345 EP2ASHFH items 1 apa 0 default asc 1 160300 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/ %7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-96fafb1fcd56e98c613534c352fc8ae3%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22EP2ASHFH%22%2C%22library%22%3A%7B%22id%22%3A6606345%7D%2C%22meta%22%3A%7B%22numChildren%22%3A0%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3E%3Ci%3EGli2-regulated%20activation%20of%20hepatic%20stellate%20cells%20and%20liver%20fibrosis%20by%20TGF-%26%23x3B2%3B%20signaling%20%7C%20American%20Journal%20of%20Physiology-Gastrointestinal%20and%20Liver%20Physiology%3C%5C%2Fi%3E.%20%28n.d.%29.%20Retrieved%20March%2019%2C%202021%2C%20from%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fjournals.physiology.org%5C%2Fdoi%5C%2Fabs%5C%2F10.1152%5C%2Fajpgi.00310.2020%3Frfr_dat%3Dcr_pub%2B%2B0pubmed%26url_ver%3DZ39.88-2003%26rfr_id%3Dori%253Arid%253Acrossref.org%27%3Ehttps%3A%5C%2F%5C%2Fjournals.physiology.org%5C%2Fdoi%5C%2Fabs%5C%2F10.1152%5C%2Fajpgi.00310.2020%3Frfr_dat%3Dcr_pub%2B%2B0pubmed%26url_ver%3DZ39.88-2003%26rfr_id%3Dori%253Arid%253Acrossref.org%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D6606345%26amp%3Bitem_key%3DEP2ASHFH%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22webpage%22%2C%22title%22%3A%22Gli2-regulated%20activation%20of%20hepatic%20stellate%20cells%20and%20liver%20fibrosis%20by%20TGF-%5Cu03b2%20signaling%20%7C%20American%20Journal%20of%20Physiology-Gastrointestinal%20and%20Liver%20Physiology%22%2C%22creators%22%3A%5B%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fjournals.physiology.org%5C%2Fdoi%5C%2Fabs%5C%2F10.1152%5C%2Fajpgi.00310.2020%3Frfr_dat%3Dcr_pub%2B%2B0pubmed%26url_ver%3DZ39.88-2003%26rfr_id%3Dori%253Arid%253Acrossref.org%22%2C%22language%22%3A%22%22%2C%22deleted%22%3A1%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-03-19T18%3A02%3A49Z%22%7D%7D%5D%7DGli2-regulated activation of hepatic stellate cells and liver fibrosis by TGF-β signaling | American Journal of Physiology-Gastrointestinal and Liver Physiology. (n.d.). Retrieved March 19, 2021, from
https://journals.physiology.org/doi/abs/10.1152/ajpgi.00310.2020?rfr_dat=cr_pub++0pubmed&url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org Cite