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Pulmonary Cell NewsResearchers suggest that HHIP repressed aerobic glycolysis and airway smooth muscle cells hyperplasia, which might contribute to the increased airway remodeling in Hhip+/- mice.
[Scientific Reports]
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Li, Y., Zhang, L., Polverino, F., Guo, F., Hao, Y., Lao, T., Xu, S., Li, L., Pham, B., Owen, C. A., & Zhou, X. (2021). Hedgehog interacting protein (HHIP) represses airway remodeling and metabolic reprogramming in COPD-derived airway smooth muscle cells. Scientific Reports, 11(1), 9074. https://doi.org/10.1038/s41598-021-88434-x Cite
