Longitudinal Single-Cell Profiling Reveals Molecular Heterogeneity and Tumor-Immune Evolution in Refractory Mantle Cell Lymphoma

By
Justin.choi
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The authors characterized the cellular and molecular heterogeneity within and across patients and delineate the dynamic evolution of tumor and immune cell compartments at single cell resolution in longitudinal specimens from ibrutinib-sensitive patients and non-responders.
[Nature Communications]
Zhang, S., Jiang, V. C., Han, G., Hao, D., Lian, J., Liu, Y., Zhang, R., McIntosh, J., Wang, R., Dang, M., Dai, E., Wang, Y., Santos, D., Badillo, M., Leeming, A., Chen, Z., Hartig, K., Bigcal, J., Zhou, J., … Wang, M. (2021). Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma. Nature Communications, 12(1), 2877. https://doi.org/10.1038/s41467-021-22872-z Cite
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