CD52 Is a Novel Target for the Treatment of FLT3-ITD-Mutated Myeloid Leukemia

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To explore alternative therapeutics to internal tandem duplication (ITD) of FMS-like tyrosine kinase 3 (FLT3), researchers established a cellular model of monoallelic FLT3ITD/WT cells using the CRISPR-Cas9 system in a human myeloid leukemia cell line.
[Cell Death Discovery]

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