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Pulmonary Cell NewsResearchers compared the ability of regulatory T cells (Treg) + mesenchymal stromal cells (MSC) combination therapy, as well as MSC and Treg monotherapies, to improve blood brain barrier permeability in vivo and suppress inflammation in vitro.
[PLOS One]
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Caplan, H. W., Prabhakara, K. S., Furman, N. E. T., Zorofchian, S., Martin, C., Xue, H., Olson, S. D., & Jr, C. S. C. (2021). Human-derived Treg and MSC combination therapy may augment immunosuppressive potency in vitro, but did not improve blood brain barrier integrity in an experimental rat traumatic brain injury model. PLOS ONE, 16(5), e0251601. https://doi.org/10.1371/journal.pone.0251601 Cite
