Differential Effects of Estradiol and Progesterone on Human T Cell Activation In Vitro

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Researchers reported a direct comparison of E2- and P4-mediated effects on human CD4+ T cells, key cells in immune regulation. T cells were stimulated to obtain different levels of activation and exposed to a broad range of hormone concentrations.
[European Journal of Immunology]
Papapavlou, G., Hellberg, S., Raffetseder, J., Brynhildsen, J., Gustafsson, M., Jenmalm, M. C., & Ernerudh, J. (n.d.). Differential effects of estradiol and progesterone on human T cell activation in vitro. European Journal of Immunology, n/a(n/a). https://doi.org/10.1002/eji.202049144 Cite
Abstract