Hsa_circ_0026628 Promotes the Development of Colorectal Cancer by Targeting SP1 to Activate the Wnt/β-Catenin Pathway

Scientists investigated the role of circular RNA (circRNAs) which shared the same pre-mRNA with Sp1 transcription factor (SP1) in colorectal cancer (CRC) cells and identified that hsa_circ_0026628, a circRNA that originated from SP1 pre-mRNA, was upregulated in CRC cells.