ZFP91 Disturbs Metabolic Fitness and Antitumor Activity of Tumor-Infiltrating T Cells

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Scientists demonstrated that ZFP91 perturbed T cell metabolic and functional states in the TME and suggested that targeting ZFP91 may improve the efficacy of cancer immunotherapy.
[Journal of Clinical Investigation]
Wang, F., Zhang, Y., Yu, X., Teng, X.-L., Ding, R., Hu, Z., Wang, A., Wang, Z., Ye, Y., & Zou, Q. (2021). ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells. The Journal of Clinical Investigation. https://doi.org/10.1172/JCI144318 Cite
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