Benzimidazoles Induce Concurrent Apoptosis and Pyroptosis of Human Glioblastoma Cells via Arresting Cell Cycle

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By analyzing the hub genes of glioblastoma multiforme (GBM) via weighted gene co-expression network analysis of the cancer genome atlas dataset, and using the connectivity map platform for drug repurposing, scientists found that multiple azole compounds had potential anti-GBM activity.
[Acta Pharmacologica Sinica]
Abstract