Rare t(X; 14)(q28; q32) Translocation Reveals Link between MTCP1 and Chronic Lymphocytic Leukemia

Scientists reported overexpression of human mature T cell proliferation 1 gene (MTCP1) restricted to the B cell compartment in mice produced a clonal CD5+/CD19+ leukemia recapitulating the major characteristics of human chronic lymphocytic leukemia.