Delayed Antiretroviral Therapy in HIV-Infected Individuals Leads to Irreversible Depletion of Skin- and Mucosa-Resident Memory T Cells

By
Justin.choi
-
0
51
Scientists found that skin CD4+ tissue-resident memory T cells were depleted after HIV infection and replenished only upon early antiretroviral therapy initiation.
[Immunity]
Saluzzo, S., Pandey, R. V., Gail, L. M., Dingelmaier-Hovorka, R., Kleissl, L., Shaw, L., Reininger, B., Atzmüller, D., Strobl, J., Touzeau-Römer, V., Beer, A., Staud, C., Rieger, A., Farlik, M., Weninger, W., Stingl, G., & Stary, G. (2021). Delayed antiretroviral therapy in HIV-infected individuals leads to irreversible depletion of skin- and mucosa-resident memory T cells. Immunity, 0(0). https://doi.org/10.1016/j.immuni.2021.10.021 Cite
AbstractGraphical Abstract