IRAK1-Regulated IFN-γ Signaling Induces MDSC to Facilitate Immune Evasion in FGFR1-Driven Hematological Malignancies

CRISPR/Cas9 approaches were used to generate stem cell leukemia/lymphoma syndrome cells null for Interleukin receptor associated kinase 1 and interferon gamma which were introduced into syngeneic hosts through tail vein injection.