A Novel CD34-Specific T-cell Engager Efficiently Depletes Acute Myeloid Leukemia and Leukemic Stem Cells In Vitro and In Vivo

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Researchers designed a CD34/CD3 bispecific T-cell engager (BiTE) and characterized its anti-leukemia potential in vitro, ex vivo and in vivo.
[Haematologica]
Abstract