Anti-Glioblastoma Effects of Phenolic Variants of Benzoylphenoxyacetamide (BPA) with High Potential for Blood Brain Barrier Penetration

Nine compounds demonstrated desirable glioblastoma cell toxicity in cell culture, and two of them, HR51, and HR59 demonstrated significantly improved capability of crossing the model blood–brain-barrier composed of endothelial cells, astrocytes and pericytes.