A Biliary Immune Landscape Map of Primary Sclerosing Cholangitis Reveals a Dominant Network of Neutrophils and Tissue-Resident T Cells

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By combining endoscopy-guided sampling of the biliary tree with a high-dimensional analysis approach, comprehensive mapping of the human biliary immunological landscape in patients with primary sclerosing cholangitis, a severe biliary inflammatory disease, was conducted.
[Science Translational Medicine]

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Abstract