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Pulmonary Cell NewsBy combining endoscopy-guided sampling of the biliary tree with a high-dimensional analysis approach, comprehensive mapping of the human biliary immunological landscape in patients with primary sclerosing cholangitis, a severe biliary inflammatory disease, was conducted.
[Science Translational Medicine]
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Zimmer, C. L., Seth, E. von, Buggert, M., Strauss, O., Hertwig, L., Nguyen, S., Wong, A. Y. W., Zotter, C., Berglin, L., Michaëlsson, J., Hansson, M. R., Arnelo, U., Sparrelid, E., Ellis, E. C. S., Söderholm, J. D., Keita, Å. V., Holm, K., Özenci, V., Hov, J. R., … Björkström, N. K. (2021). A biliary immune landscape map of primary sclerosing cholangitis reveals a dominant network of neutrophils and tissue-resident T cells. Science Translational Medicine, 13(599). https://doi.org/10.1126/scitranslmed.abb3107 Cite
