Targeted Delivery of Regulatory Macrophages to Lymph Nodes Interferes with T Cell Priming by Preventing the Formation of Stable Immune Synapses

By
Justin.choi
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0
177
Delivery of regulatory macrophages (Mregs) completely abolished the priming of cognate CD8 cells and strongly reduced delayed-type hypersensitivity reactions. Mreg-mediated T cell suppression requires cell-cell contact-regulated nitric oxide production.
[Cell Reports]

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