Intestinal organoids derived from mouse small intestine were treated with vitamin D3, and the effects on intestinal stemness and differentiation were evaluated using real-time PCR and immunofluorescence staining of the distinct lineage markers.
[Stem Cell Research & Therapy]
6445212 HNSNF8PP items 1 apa 0 default asc 1 162505 https://www.stemcellsciencenews.com/wp-content/plugins/zotpress/ %7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3A%22zotpress-c0ab7e618bb95e89636212859c1ed892%22%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22HNSNF8PP%22%2C%22library%22%3A%7B%22id%22%3A6445212%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Sittipo%20et%20al.%22%2C%22parsedDate%22%3A%222021-05-13%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%202%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESittipo%2C%20P.%2C%20Kim%2C%20H.%20K.%2C%20Han%2C%20J.%2C%20Lee%2C%20M.%20R.%2C%20%26amp%3B%20Lee%2C%20Y.%20K.%20%282021%29.%20Vitamin%20D3%20suppresses%20intestinal%20epithelial%20stemness%20via%20ER%20stress%20induction%20in%20intestinal%20organoids.%20%3Ci%3EStem%20Cell%20Research%20%26amp%3B%20Therapy%3C%5C%2Fi%3E%2C%20%3Ci%3E12%3C%5C%2Fi%3E%281%29%2C%20285.%20%3Ca%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs13287-021-02361-2%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs13287-021-02361-2%3C%5C%2Fa%3E%20%3Ca%20title%3D%27Cite%20in%20RIS%20Format%27%20class%3D%27zp-CiteRIS%27%20href%3D%27https%3A%5C%2F%5C%2Fwww.stemcellsciencenews.com%5C%2Fwp-content%5C%2Fplugins%5C%2Fzotpress%5C%2Flib%5C%2Frequest%5C%2Frequest.cite.php%3Fapi_user_id%3D6445212%26amp%3Bitem_key%3DHNSNF8PP%27%3ECite%3C%5C%2Fa%3E%20%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Vitamin%20D3%20suppresses%20intestinal%20epithelial%20stemness%20via%20ER%20stress%20induction%20in%20intestinal%20organoids%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Panida%22%2C%22lastName%22%3A%22Sittipo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hyun%20Kyu%22%2C%22lastName%22%3A%22Kim%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jaeseok%22%2C%22lastName%22%3A%22Han%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Man%20Ryul%22%2C%22lastName%22%3A%22Lee%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yun%20Kyung%22%2C%22lastName%22%3A%22Lee%22%7D%5D%2C%22abstractNote%22%3A%22Vitamin%20D3%20is%20important%20for%20normal%20function%20of%20the%20intestinal%20epithelial%20cells%20%28IECs%29.%20In%20this%20study%2C%20we%20aimed%20to%20investigate%20the%20effects%20of%20vitamin%20D3%20on%20the%20differentiation%2C%20stemness%2C%20and%20viability%20of%20healthy%20IECs%20in%20intestinal%20organoids.%22%2C%22date%22%3A%22May%2013%2C%202021%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1186%5C%2Fs13287-021-02361-2%22%2C%22ISSN%22%3A%221757-6512%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs13287-021-02361-2%22%2C%22collections%22%3A%5B%5D%2C%22dateModified%22%3A%222021-05-19T23%3A35%3A07Z%22%7D%7D%5D%7DSittipo, P., Kim, H. K., Han, J., Lee, M. R., & Lee, Y. K. (2021). Vitamin D3 suppresses intestinal epithelial stemness via ER stress induction in intestinal organoids.
Stem Cell Research & Therapy,
12(1), 285.
https://doi.org/10.1186/s13287-021-02361-2 Cite 
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News