Natural killer cells were isolated from human umbilical cord blood from a healthy newborn and reprogrammed by episomal vectors carrying reprograming factors L-MYC, LIN28, OCT4, SOX2, KLF4, EBNA-1, and shRNA against p53 delivered using nucleofection.
[Stem Cell Research]
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Klaihmon, P., Luanpitpong, S., Lorthongpanich, C., Laowtammathron, C., Waeteekul, S., Terbto, P., & Issaragrisil, S. (2021). Episomal vector reprogramming of human umbilical cord blood natural killer cells to an induced pluripotent stem cell line MUSIi013-A. Stem Cell Research, 55, 102472. https://doi.org/10.1016/j.scr.2021.102472 Cite