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Pulmonary Cell NewsInhibition of senescence-induced upregulation of hypoxia-inducible factor-2α expression during matrix maturation, but not during the proliferation stage of osteoblast differentiation, reversed the age-related decrease in Runx2 and Ocn expression.
[Experimental and Molecular Medicine]
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Lee, S. Y., Park, K. H., Lee, G., Kim, S.-J., Song, W.-H., Kwon, S.-H., Koh, J.-T., Huh, Y. H., & Ryu, J.-H. (2021). Hypoxia-inducible factor-2α mediates senescence-associated intrinsic mechanisms of age-related bone loss. Experimental & Molecular Medicine, 1–14. https://doi.org/10.1038/s12276-021-00594-y Cite
