Multimodal Single-Cell Omics Analysis Identifies Epithelium–Immune Cell Interactions and Immune Vulnerability Associated with Sex Differences in COVID-19

Investigators inspected sex differences in SARS-CoV-2 infection, hospitalization, admission to the intensive care unit (ICU), sera inflammatory biomarker profiling, and single-cell RNA-sequencing profiles across nasal, bronchoalveolar lavage fluid, and peripheral blood mononuclear cells from COVID-19 patients with varying degrees of disease severities.