Autophagic Secretion of HMGB1 from Cancer-Associated Fibroblasts Promotes Metastatic Potential of Non-Small Cell Lung Cancer Cells via NFκB Signaling

Researchers reported that autophagy was upregulated in lung cancer-associated cancer-associated fibroblasts (CAFs) compared to normal fibroblasts, and autophagy was responsible for the promoting effect of CAFs on non-small cell lung cancer cell migration and invasion.