Brain-Derived Neurotrophic Factor Promotes Immune Reconstitution Following Radiation Injury via Activation of Bone Marrow Mesenchymal Stem Cells

Brain-derived neurotrophic factor promoted hematopoietic regeneration via activation of PDGFRα+ bone marrow MSCs which increased secretion of hematopoietic cytokines interleukin 6 and leukemia inhibitory factor in response to TrkB activation.