CD157 Signaling Promotes Survival of Acute Myeloid Leukemia Cells and Modulates Sensitivity to Cytarabine through Regulation of Anti-apoptotic Mcl-1

Investigators used peripheral blood and bone marrow samples from patients with acute myeloid leukemia (AML) to analyze the impact of CD157-directed antibodies in AML survival and in response to cytarabine ex vivo.